Blood & Chrome is set during the First Cylon War, which takes place between the shows Caprica and Battlestar Galactica and the end of which was depicted in the 2007 webisode series, Razor Flashbacks. The main character will be William Adama, and one other character from Razor Flashbacks will also be featured. The rest of the characters will be new.

Battlestar Galactica: Blood & Chrome takes place in the 10th year of the first Cylon war. As the battle between humans and their creation, a sentient robotic race, rages across the 12 colonial worlds, a brash rookie viper pilot enters the fray. Ensign William Adama, barely in his 20s and a recent Academy graduate, finds himself assigned to the newest battlestar in the Colonial fleet… the Galactica. The talented but hot-headed risk-taker soon finds himself leading a dangerous top secret mission that, if successful, will turn the tide of the decade long war in favor of the desperate fleet.